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TFG mutation induces haploinsufficiency and drives axonal Charcot-Marie-Tooth disease by causing neurite degeneration.

Xihui ChenFangfang LiuKun ChenYufeng WangAn-An YinXiaowei KangShanming YangHanwen ZhaoSongqi DongYunqing LiJing ChenYuanming Wu
Published in: CNS neuroscience & therapeutics (2022)
CMT2-related TFG mutation induces TFG haploinsufficiency within cells and drives disease by causing progressive neurite degeneration.
Keyphrases
  • induced apoptosis
  • multiple sclerosis
  • spinal cord injury
  • cell cycle arrest
  • cell death
  • cell proliferation
  • drug induced