Effects of ketamine optical isomers, psilocybin, psilocin and norpsilocin on time estimation and cognition in rats.

Piotr Popik Adam S Hogendorf Ryszard Bugno Shaun Yon-Seng Khoo Paweł Zajdel Natalia Malikowska-Racia Agnieszka Nikiforuk Joanna Golebiowska

Published in: Psychopharmacology (2022)

Time underestimation produced by (S)-ketamine could be associated with its antidepressant effects; however, it was accompanied with severe behavioral disruption. We also hypothesize that behavioral disruption produced by psychedelics objectively reflects their psychotomimetic-like actions.

Keyphrases

pain management
major depressive disorder
physical activity
high resolution
mild cognitive impairment
high speed
white matter
chronic pain
mass spectrometry
drug induced