Reproducible quantification of cardiac sympathetic innervation using graphical modeling of carbon-11-meta-hydroxyephedrine kinetics with dynamic PET-CT imaging.
Tong WangKai Yi WuRobert C MinerJennifer M RenaudRob S B BeanlandsRobert A deKempPublished in: EJNMMI research (2018)
Logan and MA1 models exhibited similar agreement and variability compared to the 1TC for modeling of [11C]HED kinetics. Using t* = 5 min and partial-volume correction produced accurate estimates of VT as an index of myocardial sympathetic innervation.