A Phase III Study to Compare the Efficacy and Safety of Paclitaxel Versus Irinotecan in Patients with Metastatic or Recurrent Gastric Cancer Who Failed in First-line Therapy (KCSG ST10-01).
Keun-Wook LeeChi Hoon MaengTae-You KimDae Young ZangYeul Hong KimIn Gyu HwangSang Cheul OhJoo Seop ChungHong Suk SongJin Won KimSu Jin JeongJae Yong ChoPublished in: The oncologist (2018)
Although paclitaxel showed numerically longer PFS and OS compared with irinotecan, this was statistically insignificant. Both irinotecan and paclitaxel are valid second-line treatment options in MRGC.