Mitochondrial content, activity, and morphology in prepubertal and adult human ovaries.

Rossella MasciangeloMaria Costanza ChitiAlessandra CamboniChristiani Andrade AmorimJacques DonnezMarie-Madeleine Dolmans

Published in: Journal of assisted reproduction and genetics (2021)

Differences in the number, activity, and morphology of mitochondria were reported, suggesting that consequential modifications might occur during puberty, which could be the window of opportunity required by mitochondria to undergo changes needed to reach maturity, and hence the capacity for ovulation and fertilization.

Keyphrases

endothelial cells
cell death
reactive oxygen species
oxidative stress
endoplasmic reticulum
polycystic ovary syndrome
type diabetes
induced pluripotent stem cells
insulin resistance
childhood cancer