Novel Risk Loci Identified in a Genome-Wide Association Study of Urolithiasis in a Japanese Population.

Chizu TanikawaYoichiro KamataniChikashi TeraoMasayuki UsamiAtsushi TakahashiYukihide MomozawaKichiya SuzukiSoichi OgishimaAtsushi ShimizuMamoru SatohKeitaro MatsuoHaruo MikamiMariko NaitoKenji WakaiTaiki YamajiNorie SawadaMotoki IwasakiShoichiro TsuganeKenjiro KohriAlan S L YuTakahiro YasuiYoshinori MurakamiMichiaki KuboKoichi Matsuda

Published in: Journal of the American Society of Nephrology : JASN (2019)

Our findings provide evidence that host genetic factors related to regulation of metabolic and crystallization pathways contribute to the development of urolithiasis.

Keyphrases

genome wide association study
genome wide
copy number
gene expression
dna methylation