Plasma NT1-tau and Aβ 42 correlate with age and cognitive function in two large Down syndrome cohorts.
Andrew M SternKathryn L Van PeltLei LiuAmirah K AndersonBeth OstaszewskiMark MapstoneSid O'BryantMelissa E PetersenBradley T ChristianBenjamin L HandenDennis J SelkoeFrederick SchmittElizabeth Headnull nullPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2023)
NT1-tau correlates with age and worse cognition in DS. Further validation of NT1-tau and other plasma biomarkers of AD neuropathology in DS cohorts is important for clinical utility.