Neutrophils as key regulators of tumor immunity that restrict immune checkpoint blockade in liver cancer.
Mei FengFangyanni WangXinyu LiuTingting HaoNing ZhangMi DengYisheng PanRuirui KongPublished in: Cancer biology & medicine (2023)
Our data suggest that TANs may contribute to the resistance of liver cancer to ICB, and combining TAN depletion with T cell immunotherapy synergistically increases antitumor efficacy.