Three days of HFD-induced epigenomic and transcriptomic changes involving metabolic and immunologic pathways that may promote tumor growth in the genetically predisposed murine intestine without affecting key cancer signaling pathways.
Keyphrases
- high fat diet
- insulin resistance
- adipose tissue
- papillary thyroid
- high fat diet induced
- signaling pathway
- high glucose
- dna methylation
- diabetic rats
- gene expression
- single cell
- pi k akt
- rna seq
- squamous cell carcinoma
- oxidative stress
- induced apoptosis
- cell proliferation
- young adults
- endoplasmic reticulum stress
- wild type