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Immune Regulation of TNFAIP3 in Psoriasis through Its Association with Th1 and Th17 Cell Differentiation and p38 Activation.

Yanyun JiangWenming WangXiaofeng ZhengHong-Zhong Jin
Published in: Journal of immunology research (2020)
TNFAIP3 downregulation associated with Th1 and Th17 cell differentiation and p38 activation might contribute in part to the mechanism of immune dysfunction in psoriasis. TNF-α antagonists might partly exert their effects on psoriasis via this pathway.
Keyphrases
  • atopic dermatitis
  • rheumatoid arthritis
  • cell proliferation
  • oxidative stress
  • signaling pathway