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Development of Predictive Models to Inform a Novel Risk Categorization Framework for Antibiotic Resistance in Escherichia coli-Caused Uncomplicated Urinary Tract Infection.

Ryan K ShieldsWendy Y ChengKalé Kponee-ShoveinDaniel IndacocheaChi GaoFernando KuwerAshish V JoshiFanny S Mitrani-GoldPatrick SchwabDiogo FerrinhoMalena MahendranLisa PinheiroJimmy RoyerMadison T PreibJennifer HanRichard Colgan
Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2024)
Our predictive models highlight factors that increase risk of nonsusceptibility to antibiotics for uUTIs, while the risk categorization framework contextualizes risk of nonsusceptibility to these treatments. Our findings provide valuable insight to clinicians treating uUTIs and may help inform empiric prescribing in this population.
Keyphrases
  • urinary tract infection
  • escherichia coli
  • primary care
  • emergency department
  • staphylococcus aureus
  • cystic fibrosis
  • pseudomonas aeruginosa
  • biofilm formation
  • klebsiella pneumoniae
  • drug induced