Inhibition of TLR4 signaling protects mice from sensory and motor dysfunction in an animal model of autoimmune peripheral neuropathy.
Oladayo OladiranXiang Qun ShiMu YangSylvie FournierJi ZhangPublished in: Journal of neuroinflammation (2021)
The study identified the critical contribution of TLR4-mediated macrophage activation in disease course and provided strong evidence to support TLR4 as a useful drug target for treating inflammatory autoimmune neuropathy.