Inhibition of TLR4 signaling protects mice from sensory and motor dysfunction in an animal model of autoimmune peripheral neuropathy.

Oladayo OladiranXiang Qun ShiMu YangSylvie FournierJi Zhang

Published in: Journal of neuroinflammation (2021)

The study identified the critical contribution of TLR4-mediated macrophage activation in disease course and provided strong evidence to support TLR4 as a useful drug target for treating inflammatory autoimmune neuropathy.

Keyphrases

toll like receptor
inflammatory response
immune response
multiple sclerosis
oxidative stress
nuclear factor
drug induced
type diabetes
emergency department
adverse drug