Neuronal Nitric Oxide Synthase Is a Novel Biomarker for the Interstitial Cells of Cajal in Stress-Induced Diarrhea-Dominant Irritable Bowel Syndrome.

Da Eun JangJi Hyun BaeYoo Jin ChangYoon Hoo LeeKi Taek NamIl Yong KimJe Kyung SeongYong Chan LeeSu Cheong Yeom

Published in: Digestive diseases and sciences (2018)

Our study demonstrates that early-life stress can influence to ICC and modulate bowel activity and that nNOS might be used as a biomarker for ICC stimulation in IBS.

Keyphrases

irritable bowel syndrome
stress induced
nitric oxide synthase
early life
nitric oxide
induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
cell death
cell proliferation
oxidative stress
blood brain barrier