A Leep1 into migration and macropinocytosis.

Published in: The Journal of cell biology (2021)

Actin organization underpins conserved functions at the leading edge of cells. In this issue, Yang et al. (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202010096) characterize Leep1 as a bi-functional regulator of migration and macropinocytosis through PIP3 and the Scar/WAVE complex.

Keyphrases

induced apoptosis
transcription factor
cell cycle arrest
single cell
cell therapy
endoplasmic reticulum stress
signaling pathway
cell death
mesenchymal stem cells
pi k akt