Self-Amplified pH/ROS Dual-Responsive Co-Delivery Nano-System with Chemo-Photodynamic Combination Therapy in Hepatic Carcinoma Treatment.

Yu Huang Shuyang WuJingjing LiChenglin HeYanfen ChengNan LiYitao WangYihan WuJinming Zhang

Published in: International journal of nanomedicine (2024)

Overall, we have developed a tumor microenvironment-responsive nanosystem for the co-delivery of TPL and Ce6, demonstrating amplified synergistic effects of chemo-photodynamic therapy (chemo-PDT) for hepatocellular carcinoma (HCC) treatment.

Keyphrases

combination therapy
photodynamic therapy
cancer therapy
fluorescence imaging
drug delivery
dna damage
cell death
reactive oxygen species