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Assessment of prolonged proteasome inhibition through ixazomib-based oral regimen on newly diagnosed and first-relapsed multiple myeloma: A real-world Chinese cohort study.

Aijun LiuHong YuRui HouZunmin ZhuJun-Ling ZhuangLi BaoZhenling LiLihong LiuLuoming HuaYanping MaDa GaoArong JinXiaohui SuoWei YangYuansong BaiRong FuDeqiang ZhengWenming Chen
Published in: Cancer medicine (2024)
In the real-world Chinese MM population, NDMM and FRMM patients responded favorably to PI-based continuous therapy, demonstrating substantial response rates. The ixazomib-based iCT allows for sustained PI-based treatment, offering promising efficacy and tolerable AEs.
Keyphrases
  • newly diagnosed
  • multiple myeloma
  • end stage renal disease
  • chronic kidney disease
  • ejection fraction
  • acute myeloid leukemia
  • peritoneal dialysis
  • prognostic factors
  • stem cells
  • bone marrow
  • mesenchymal stem cells