Assessment of prolonged proteasome inhibition through ixazomib-based oral regimen on newly diagnosed and first-relapsed multiple myeloma: A real-world Chinese cohort study.
Aijun LiuHong YuRui HouZunmin ZhuJun-Ling ZhuangLi BaoZhenling LiLihong LiuLuoming HuaYanping MaDa GaoArong JinXiaohui SuoWei YangYuansong BaiRong FuDeqiang ZhengWenming ChenPublished in: Cancer medicine (2024)
In the real-world Chinese MM population, NDMM and FRMM patients responded favorably to PI-based continuous therapy, demonstrating substantial response rates. The ixazomib-based iCT allows for sustained PI-based treatment, offering promising efficacy and tolerable AEs.