Osteoprotegerin increases parallel to insulin resistance in obese adolescents.
Eleni P KotanidouChristos P KotanidisStyliani GizaAnastasios SerbisVasiliki-Regina TsinopoulouParaskevi KaralazouGeorgios TzimagiorgisAssimina Galli-TsinopoulouPublished in: Endocrine research (2018)
Obese individuals demonstrate increased serum OPG levels during puberty. Obesity per se is not the potent factor for this increase; indeed, IR accompanying obesity seems to exert a fundamental role in OPG upregulation.