Intrahepatic Cholangiocarcinoma with Lymph Node Metastasis: Treatment-Related Outcomes and the Role of Tumor Genomics in Patient Selection.
Joshua S JolissaintKevin C SoaresKenneth P SeierRitika KundraMithat GönenPaul J ShinThomas BoernerCarlie S SigelRamyasree MadupuriEfsevia VakianiAndrea CercekJames J HardingNancy E KemenyLouise C ConnellVinod P BalachandranMichael I D'AngelicaJeffrey A DrebinT Peter KinghamAlice C WeiWilliam R JarnaginPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
There was no difference in OS for patients with node-positive IHC treated by resection versus HAIC, and both treatments had better survival than SYS alone. The presence of high-risk genetic alterations provides valuable prognostic information that may help guide treatment.