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Priming Leukemia with 5-Azacytidine Enhances CAR T Cell Therapy.

Ning XuBenjamin TseLu YangTiffany C Y TangMichelle HaberKenneth MicklethwaiteAlla Dolnikov
Published in: ImmunoTargets and therapy (2021)
We propose that treatment with AZA activates OX40L/OX40 co-stimulatory signaling in CAR T cells. Our data suggest that the clinical use of AZA before CAR T cells could be considered.
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