Neurite Orientation Dispersion and Density Imaging for Assessing Acute Inflammation and Lesion Evolution in MS.
Simone SaccoEduardo CaverzasiNico PapinuttoChristian CordanoAntje BischofT GundelS ChengCarlo AsteggianoGina KirkishJacob M MallottWilliam A SternStefano BastianelloRiley M BoveJeffrey Marc GelfandDouglas S GoodinAri J GreenEmmanuelle WaubantMichael R WilsonScott S ZamvilBruce Anthony Campbell CreeStephen L HauserRoland G Henrynull nullPublished in: AJNR. American journal of neuroradiology (2020)
NODDI is a promising tool with the potential to detect acute MS inflammation. The observed heterogeneity among lesions may correspond to gradients in severity and clinical recovery after the acute phase.