The ability of post-chemoradiotherapy DWI ADCmean and 18F-FDG SUVmax to predict treatment outcomes in head and neck cancer: impact of human papilloma virus oropharyngeal cancer status.
Steve E J ConnorC SitM AnjariM LeiT Guerrero-UrbanoT SzyszkoG CookP BassettV GohPublished in: Journal of cancer research and clinical oncology (2021)
Absolute post-CRT ADCmean values predicted DFS in HNSCC but not in the HPV-OPC subgroup. Amongst participants with DFS, post-CRT percentage interval changes in primary tumour ADCmean were significantly higher in HPV-OPC than in other HNSCC. Knowledge of HPV-OPC status is crucial to the clinical utilisation of post-CRT DWI-MRI for the prediction of outcomes.
Keyphrases
- high grade
- cardiac resynchronization therapy
- diffusion weighted imaging
- endothelial cells
- magnetic resonance imaging
- healthcare
- clinical trial
- rectal cancer
- type diabetes
- cervical cancer screening
- pet ct
- left ventricular
- insulin resistance
- contrast enhanced
- papillary thyroid
- metabolic syndrome
- positron emission tomography
- young adults
- open label
- skeletal muscle
- childhood cancer
- study protocol