Canonical notch activation in patients with scrub typhus: association with organ dysfunction and poor outcome.
Jan K DamåsKari OtterdalElisabeth AstrupTove LekvaJeshina JanardhananAnnika MichelsenPål AukrustGeorge M VargheseThor Ueland
Published in: Infection (2024)
Our findings suggest that scrub typhus patients are characterized by enhanced canonical Notch activation. Elevated plasma levels of DLL1 were associated with organ dysfunction and poor outcomes in these patients.