Chemotherapy-induced infiltration of neutrophils promotes pancreatic cancer metastasis via Gas6/AXL signalling axis.
Gaia BellomoCarolyn RainerValeria QuarantaYuliana AstutiMeirion RaymantElzbieta BoydRuth StaffertonFiona CampbellPaula GhanehChristopher M HalloranDean E HammondJennifer P MortonDaniel PalmerDale VimalachandranRobert JonesAinhoa MielgoMichael C SchmidPublished in: Gut (2022)
Combining chemotherapy with Gas6/AXL or neutrophil targeted therapy could provide a therapeutic benefit for patients with metastatic pancreatic cancer.