Development of a method for clinical pharmacokinetic testing to allow for targeted Melphalan dosing in multiple myeloma patients undergoing autologous transplant.

Karen I SweissBhaskar VemuCraig C HofmeisterEric WenzlerGregory Sampang CalipJohn P GalvinNadim MahmudDamiano RondelliJeremy James JohnsonPritesh Patel

Published in: British journal of clinical pharmacology (2020)

Here we outline the methods to establish novel melphalan dosing using PK testing in MM patients undergoing ASCT to target a desired melphalan AUC.

Keyphrases

patients undergoing
high dose
multiple myeloma
low dose
bone marrow
cancer therapy
cell therapy
stem cells
mesenchymal stem cells