Methylation silencing of ULK2 via epithelial-mesenchymal transition causes transformation to poorly differentiated gastric cancers.

Iori MotooSohachi NanjoTakayuki AndoSatoshi YamashitaToshikazu UshijimaIchiro Yasuda

Published in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2021)

Methylation silencing of ULK2 could induce cell migration and EMT by means of autophagy induction, causing transformation to poorly differentiated cancers.

Keyphrases

epithelial mesenchymal transition
cell migration
signaling pathway
genome wide
transforming growth factor
dna methylation
cell death
oxidative stress
endoplasmic reticulum stress
gene expression