Risk Factors for SARS-CoV-2 Infection and Severe Outcomes Among People With Human Immunodeficiency Virus: Cohort Study.
John J HannaLiyu B GeresuMarlon I DiazMilan HoJulia A CasazzaMadison A PickeringHeather D LanierAlexander P RadunskyLauren N CooperSameh N SalehRoger J BedimoZachary M MostTrish M PerlChristoph U LehmannRobert W TurerJeremy Y ChowRichard J MedfordPublished in: Open forum infectious diseases (2023)
This large US study found significant ethnic, racial, and geographic differences in SARS-CoV-2 infection among PWH. Chronic comorbidities, older age, lower body mass index, and smoking were associated with severe outcomes among PWH during the COVID-19 pandemic. SARS-CoV-2 infection was associated with severe outcomes, but once we adjusted for HIV care variables, SARS-CoV-2 was no longer significant; however, low CD4 count, high viral load, and lack of antiretroviral therapy had higher odds of severe outcomes.