Association Between Maternal Serum Folate Concentrations in the First Trimester and the Risk of Birth Defects: The Hokkaido Study of Environment and Children's Health.
Kumiko ItoTomoyuki HanaokaNaomi TamuraSeiko SasakiChihiro MiyashitaAtsuko Ikeda-ArakiSachiko ItoHisanori MinakamiKazutoshi ChoToshiaki EndoTsuyoshi BabaToshinobu MiyamotoKazuo SengokuAkiko TamakoshiReiko KishiPublished in: Journal of epidemiology (2018)
We were unable to demonstrate a relationship between maternal serum folate in the first trimester and birth defects. Potential confounding factors may have influenced our results.