Prognostic factors of non-muscle invasive bladder cancer: a study based on next-generation sequencing.

Yanxiang ShaoXu HuZhen YangThongher LiaWeixiao YangKan WuShangqing RenSanchao XiongWeichao DouShuyang FengYaohui WangYang LiuKang WuXiang Li

Published in: Cancer cell international (2021)

BCG instillation significantly reduced the rate of recurrence compared with epirubicin in this population. Potential biomarkers and therapeutic targets were found with the help of next-generation sequencing; correlations between DDR genes alterations and high tumor mutation burden were also demonstrated.

Keyphrases

prognostic factors
muscle invasive bladder cancer
copy number
circulating tumor
genome wide
risk factors
genome wide identification
gene expression
transcription factor