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Association between functional FCGR3A F158V and FCGR2A R131H polymorphisms and responsiveness to rituximab in patients with autoimmune diseases: a meta-analysis.

Young Ho LeeGwan Gyu Song
Published in: The pharmacogenomics journal (2023)
We demonstrated that the FCGR3A F158V polymorphism is associated with better responsiveness to rituximab therapy in patients with autoimmune diseases, indicating that individuals carrying the FCGR3A V allele will likely respond better to rituximab. However, FCGR2A R131H polymorphism was not associated with better response to rituximab.
Keyphrases
  • diffuse large b cell lymphoma
  • chronic lymphocytic leukemia
  • hodgkin lymphoma
  • stem cells
  • mesenchymal stem cells
  • bone marrow