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Acute phase reactions in Daboia siamensis venom and fraction-induced acute kidney injury: the role of oxidative stress and inflammatory pathways in in vivo rabbit and ex vivo rabbit kidney models.

Narongsak ChaiyabutrJureeporn NoipromKanyanat PromruangreangTaksa VasaruchapongPanithi LaoungbuaOrawan KhowLawan ChanhomeVisith Sitprija
Published in: The journal of venomous animals and toxins including tropical diseases (2024)
RVV induces renal tubular toxicity by increasing oxidative stress production and elevating inflammatory cytokines in urine. During the acute phase of acute kidney injury, the balance of urine cytokines shifts toward anti-inflammatory dominance within the first two hours post-RVV and venom fractions.
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