Single-Nephron GFR in Different GBM Stages of Membranous Nephropathy.
Yusuke OkabayashiNobuo TsuboiHirokazu MarumotoTakaya SasakiKotaro HaruharaGo KanzakiKentaro KoikeHiroyuki UedaAkira ShimizuVictor G PuellesVivette D'AgatiTakashi YokooPublished in: Kidney360 (2023)
These results provide the first clinical evidence of alterations in single-nephron dynamics with advancing EC stage of human MN and support a role for disease-specific GBM structural lesions as determinants of SNGFR.