Network Pharmacology Analysis of the Mechanisms of Compound Herba Sarcandrae (Fufang Zhongjiefeng) Aerosol in Chronic Pharyngitis Treatment.

Yanping ZhangTaohua YuanYunsong LiNing WuXiaotian Dai

Published in: Drug design, development and therapy (2021)

Through a network pharmacology approach and animal study, we predicted and validated the active compounds of FFZJF and their potential targets for CP treatment. The results suggest that FFZJF can markedly alleviate GAS-induced chronic pharyngitis by modulating the TLR-4/MyD88/NF-κB signaling pathways.

Keyphrases

signaling pathway
toll like receptor
pi k akt
drug induced
nuclear factor
risk assessment
epithelial mesenchymal transition
cell proliferation
combination therapy
replacement therapy
ionic liquid