Genome-wide association study and genomic risk prediction of age-related macular degeneration in Israel.

Michelle GruninDaria TriffonGala BeykinElior RahmaniRegev SchweigerLiran TiosanoSamer KhatebShira Hagbi-LeviBatya RinskyRefael MunitzThomas W WinklerIris M HeidEran HalperinShai CarmiItay Chowers

Published in: medRxiv : the preprint server for health sciences (2023)

Previously reported AMD-associated loci were nominally associated with AMD in Israel. A PRS developed based on a large international study is predictive in Israeli populations.

Keyphrases

age related macular degeneration
genome wide association study
genome wide
copy number
dna methylation