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Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono(2-ethylhexyl) phthalate and 5-azacytidine in zebrafish.

Jorke H KamstraLiana Bastos SalesPeter AleströmJuliette Legler
Published in: Epigenetics & chromatin (2017)
Our results suggest a functional role for DNA methylation on cis-regulatory conserved elements following developmental exposure to compounds. Effects on these regions are potentially transferred to subsequent generations.
Keyphrases
  • dna methylation
  • transcription factor
  • genome wide
  • gene expression
  • mitochondrial dna