The FOXA2 transcription factor is frequently somatically mutated in uterine carcinosarcomas and carcinomas.
Matthieu Le GalloMeghan L RuddMary Ellen UrickNancy F Hansennull nullMaria J MerinoDavid G MutchPaul J GoodfellowJames C MullikinDaphne W BellPublished in: Cancer (2017)
Collectively, the findings of the current study provide compelling genetic evidence that FOXA2 is a pathogenic driver gene in the etiology of primary uterine cancers, including UCSs. Cancer 2018;124:65-73. © 2017 American Cancer Society.