Relationship between frailty, polypharmacy, and underprescription in older adults living in nursing homes.
Marta Gutiérrez-ValenciaMikel IzquierdoEsther Lacalle-FaboItxaso Marín-EpeldeMaría Fernanda Ramón-EspinozaThamara Domene-DomeneÁlvaro Casas-HerreroArkaitz GalbeteNicolás Martínez-VelillaPublished in: European journal of clinical pharmacology (2018)
The positive association found in previous studies between frailty and polypharmacy cannot be extrapolated to institutionalized populations. There is a trend towards higher rates of underprescription in frail subjects. Underprescription in frail older adults should be redefined and new strategies to measure it should be developed.