Trans-Ancestral Genetic Risk Factors for Treatment-Related Type 2 Diabetes Mellitus in Survivors of Childhood Cancer.
Cindy ImAchal NeupaneJessica L BaedkeBrian LennyAngela DelaneyStephanie B DixonEric J ChowSogol Mostoufi-MoabTianzhong YangMelissa A RichardMaria Monica J GramatgesPhilip J LupoNoha SharafeldinSmita BhatiaGregory T ArmstrongMelissa M HudsonKristen K NessLeslie L RobisonYutaka YasuiCarmen L WilsonYadav SapkotaPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Our findings suggest therapy-related genetic risks contribute to the increased T2D burden among non-Hispanic Black childhood cancer survivors. Additional study of how therapy-related genetic susceptibility contributes to this disparity is needed.