Screen identifies fasudil as a radioprotector on human fibroblasts.

Yanling YaoChen ChenZuchao CaiGuochao LiuChenxia DingDavid LimChao Dong Zhihui Feng

Published in: Toxicology research (2022)

Our study identified fasudil as a novel radioprotector that exert radioprotective effects on normal cells through regulation of DSB repair by promoting HR repair.

Keyphrases

induced apoptosis
endothelial cells
cell cycle arrest
high throughput
signaling pathway
endoplasmic reticulum stress
cell death
cell proliferation