Association of genetic variants in the IL4 and IL4R genes with the severity of joint damage in rheumatoid arthritis: a study in seven cohorts.

A KrabbenA G WilsonD P C de RooyA ZhernakovaE BrouwerE LindqvistT SaxneG StoekenJ A B van NiesR KnevelT W J HuizingaR ToesP K GregersenA H M van der Helm-van Mil

Published in: Arthritis and rheumatism (2014)

Genetic variants in IL4R were identified, and their association with the progression rate of joint damage in RA was independently replicated.

Keyphrases

rheumatoid arthritis
oxidative stress
disease activity
ankylosing spondylitis
interstitial lung disease
systemic lupus erythematosus
transcription factor
genome wide identification
idiopathic pulmonary fibrosis