Influence of sex hormone use on sleep architecture in a transgender cohort: findings from the prospective RESTED study.
Margot W L MorssinkhofYsbrand D van der WerfOdile A van den HeuvelDaan A van den EndeKarin van der TuukMartin den HeijerBirit F P BroekmanPublished in: Sleep (2023)
Sleep architecture changes after three months of masculinizing GAHT in line with sleep in cisgender males, while it shows no changes after feminizing GAHT. The sex-specific nature of these changes raises new questions on sex hormones and sleep. Future research should focus on studying possible underlying neural mechanisms and clinical consequences of these changes.