Disparities in the glycaemic and incretin responses to intraduodenal glucose infusion between healthy young men and women.
Cong XieWeikun HuangYixuan SunChunjie XiangLaurence TrahairKaren Louise JonesMichael HorowitzChristopher K RaynerChinmay S MarathePublished in: The Journal of clinical endocrinology and metabolism (2023)
Healthy young women exhibit comparable GIP but a markedly greater GLP-1 response to intraduodenal glucose than men. This disparity warrants further investigations to delineate the underlying mechanisms and may be of relevance to the reduced risk of diabetes in pre-menopausal women when compared to men.