The Late Effects of Cancer Treatment on Female Fertility and the Current Status of Fertility Preservation-A Narrative Review.
Kenny Alexandra Rodriguez-WallbergYanyu JiangTobias LekbergHanna P NilssonPublished in: Life (Basel, Switzerland) (2023)
Fertility counseling should be offered to all individuals of young reproductive age early in the patient's trajectory following a cancer diagnosis. Systemic cancer treatment and radiotherapy often have an inherent gonadotoxic effect with the potential to induce permanent infertility and premature ovarian failure. For the best chances to preserve a patient's fertility potential and to improve future quality of life, fertility preservation methods should be applied before cancer treatment initiation, thus multidisciplinary team-work and timely referral to reproductive medicine centers specialized in fertility preservation is recommended. We aim to review the current clinical possibilities for fertility preservation and summarize how infertility, as a late effect of gonadotoxic treatment, affects the growing population of young female cancer survivors.
Keyphrases
- childhood cancer
- current status
- young adults
- primary care
- palliative care
- case report
- squamous cell carcinoma
- type diabetes
- metabolic syndrome
- quality improvement
- skeletal muscle
- risk assessment
- radiation induced
- rectal cancer
- men who have sex with men
- radiation therapy
- locally advanced
- smoking cessation
- hepatitis c virus