Respiratory characteristics in children with spinal muscular atrophy type 1 receiving nusinersen.

Lena Xiao Jackie Chiang Maria Luisa Castro Codesal Hanna Katherine Kolski Prabhjot K BediFatema Al AmraniHernan D Gonorazky Reshma Aminnull null

Published in: Pediatric pulmonology (2022)

This study showed abnormal polysomnography parameters and need for ventilation despite nusinersen suggesting ongoing need for regular monitoring with polysomnography. Understanding the respiratory disease trajectory of children undergoing treatment with nusinersen will inform decision-making regarding optimal timing of ventilatory support initiation.

Keyphrases

obstructive sleep apnea
decision making
young adults
sleep apnea
intensive care unit
mechanical ventilation
extracorporeal membrane oxygenation