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Perioperative Durvalumab with Neoadjuvant Chemotherapy in Operable Bladder Cancer.

Thomas PowlesJames W F CattoMatthew D GalskyHikmat A Al-AhmadieJoshua J MeeksHiroyuki NishiyamaToan Quang VuLorenzo AntonuzzoPawel WiechnoVagif AtduevAriel Galapo KannTae-Hwan KimCristina SuárezChao-Hsiang ChangFlorian RoghmannMustafa ÖzgüroğluBernhard J EiglNiara OliveiraTomas BuchlerMoran GadotYousef ZakhariaJon ArmstrongAshok GuptaStephan HoisMichiel S van der Heijdennull null
Published in: The New England journal of medicine (2024)
Perioperative durvalumab plus neoadjuvant chemotherapy led to significant improvements in event-free survival and overall survival as compared with neoadjuvant chemotherapy alone. (Funded by AstraZeneca; NIAGARA ClinicalTrials.gov number, NCT03732677; EudraCT number, 2018-001811-59.).
Keyphrases
  • neoadjuvant chemotherapy
  • free survival
  • locally advanced
  • lymph node
  • sentinel lymph node
  • cardiac surgery
  • patients undergoing
  • rectal cancer
  • squamous cell carcinoma
  • radiation therapy
  • acute kidney injury