Association of Dual-Task Gait Cost and White Matter Hyperintensity Burden Poststroke: Results From the ONDRI.
Frederico Pieruccini-FariaBenjamin CornishMalcolm BinnsJulia FraserSeyyed M H HaddadKelly SunderlandJoel RamirezDerek BeatonDonna KwanAllison A DilliottChristopher ScottYanina Sarquis-AdamsonAlanna BlackKaren Van OoteghemLeanne CasaubonDar DowlatshahiAyman HassanJennifer MandziaDemetrios SahlasGustavo SaposnikBrian TanRobert HegeleDennis BulmanMahdi GhaniJohn RobinsonEkaterina RogaevaSali FarhanSean SymonsNuwan NanayakkaraStephen R ArnottCourtney BerezukMelissa HolmesSabrina AdamoMiracle OzzoudeMojdeh ZamyadiWendy LouSujeevini SujanthanRobert BarthaSandra E BlackRichard H SwartzWilliam McIlroyManuel Montero-OdassoPublished in: Neurorehabilitation and neural repair (2023)
In poststroke, increased DTC may be an indicator of larger white matter damages, specifically in subcortical regions, which can potentially affect the overall cognitive processing and decrease gait automaticity by increasing the cortical control over patients' locomotion.