Targeting of cadherin-11 decreases skin fibrosis in the tight skin-1 mouse model.

Mesias PedrozaRobert L WelschhansSandeep K Agarwal

Published in: PloS one (2017)

These data demonstrate an important role for CDH11 in the development of skin fibrosis in Tsk-1 mice. These data add to the growing evidence for the important role of CDH11 in tissue fibrosis and fibrotic disease such as systemic sclerosis.

Keyphrases

systemic sclerosis
interstitial lung disease
soft tissue
mouse model
wound healing
electronic health record
big data
cancer therapy
machine learning
idiopathic pulmonary fibrosis
metabolic syndrome
drug delivery
artificial intelligence
skeletal muscle
cell adhesion