A Cohort Study of the Age at Menopause in Female Patients With and Without Inflammatory Bowel Disease.
Varun P MoktanNader D DaoudWilliam J TremaineEdward V LoftusSunanda V KaneAlexander P HochwaldDavid O HodgeJana G HashashStephanie S FaubionFrancis A FarrayePublished in: Crohn's & colitis 360 (2022)
IBD is associated with an earlier onset of menopause. Although it is unclear if this mean difference of 1.5 years is clinically relevant, it is known that early menopause is associated with an increased risk of osteoporosis and cardiovascular disease. Further research on the possible mechanisms is needed.