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Asian race and origin have no clinically meaningful effects on polatuzumab vedotin pharmacokinetics in patients with relapsed/refractory B-cell non-Hodgkin lymphoma.

Rong ShiTong LuGrace KuHao DingTomohisa SaitoLeonid GibianskyPriya AgarwalXiaobin LiJin Yan JinSandhya GirishDale MilesChunze LiDan Lu
Published in: Cancer chemotherapy and pharmacology (2020)
Race has no clinically meaningful effect on pola PK. These results (and observations from efficacy/safety exposure-response analyses) support no pola dose adjustments are warranted for Asian patients with DLBCL.
Keyphrases
  • hodgkin lymphoma
  • diffuse large b cell lymphoma
  • acute lymphoblastic leukemia
  • acute myeloid leukemia
  • multiple myeloma