One novel ACOT7-NPHP4 fusion gene identified in one patient with acute lymphoblastic leukemia: a case report.

Xin ZongZhijie KangDan HuangXuehong ZhangYuan GaoHaina WangWeiling LiJin-Song Yan

Published in: BMC medical genomics (2022)

This is the first report of a patient with ALL carrying an ACOT7-NPHP4 fusion gene. These findings may help understand the impact of ACOT7-NPHP4 in clinical molecular monitoring and drug resistance to doxorubicin; furthermore, its leukemogenesis will be essential to explore in future.

Keyphrases

acute lymphoblastic leukemia
case report
copy number
genome wide
genome wide identification
drug delivery
gene expression
dna methylation
transcription factor