SCAR: The high-prevalence antigen 013.008 in the Scianna blood group system.
Kshitij SrivastavaJasem AlbasriOmar M AlsuhaibaniHassan A AljasemMarina U BuenoTania AntonacciDonald R BranchGregory Andrew DenommeWilly Albert FlegelPublished in: Transfusion (2020)
We characterized a high-prevalence antigen, with the proposed name "SCAR," which is the eighth antigen of the Scianna blood group system (proposed designation 013.008). Individuals homozygous for ERMAP:p.(Gln142Glu) protein variant can produce anti-SCAR. Although we did not observe any sign of hemolysis at this time, the anti-SCAR prompted a change of the treatment regimen. A review of the known reports indicated that all SC alloantibodies of sufficient titer should be considered capable of causing hemolysis.