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SCAR: The high-prevalence antigen 013.008 in the Scianna blood group system.

Kshitij SrivastavaJasem AlbasriOmar M AlsuhaibaniHassan A AljasemMarina U BuenoTania AntonacciDonald R BranchGregory Andrew DenommeWilly Albert Flegel
Published in: Transfusion (2020)
We characterized a high-prevalence antigen, with the proposed name "SCAR," which is the eighth antigen of the Scianna blood group system (proposed designation 013.008). Individuals homozygous for ERMAP:p.(Gln142Glu) protein variant can produce anti-SCAR. Although we did not observe any sign of hemolysis at this time, the anti-SCAR prompted a change of the treatment regimen. A review of the known reports indicated that all SC alloantibodies of sufficient titer should be considered capable of causing hemolysis.
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